Calvert’s commitment to quality, customer service, and flexibility is now extended even further with the addition of intravenous continuous infusion as part of our parenteral route of administration.
Intravenous continuous infusion is commonly used in the clinical administration of drugs such as chemotherapeutics, antibiotics, etc.. When a compound needs to be delivered by continuous infusion clinically, using intravenous continuous infusion as the preclinical route of administration is required to mimic future clinical trials.
To perform the procedure, animals are surgically implanted with in-dwelling catheters. Each animal on study requires an infusion setup consisting of a harness (which the animal wears to connect the catheter to the infusion setup), a tether that connects the infusion line to the harness and protects the infusion line from the animal, and a swivel which allows the animal to move relatively freely within the cage. These items are all purchased for each individual animal on a study by study basis. Calibrated infusion pumps are then used to control the rate of dose administration to each animal over prolonged periods of time.
When Calvert first considered adopting the continuous infusion procedure, the technology with the catheter implantations, infusion pumps and infusion setups was not as advanced as it is today. The improvements in technology have lead to an overall reduction in the number of technicians required to perform each study. This now allows us to focus more time on the individual study and communication with our clients.
By now offering continuous infusion, clients requiring this service can now have now get access to Calvert’s commitment to quality, customer service and excellent reputation in the industry, and to benefits that they may not get elsewhere.
